Volume 2, Issue 1, January 2014, Page: 5-12
Multiple Drug Resistance and ESBL Production in Bacterial Urine Culture Isolates
Riffat Iqbal, Department of Microbiology, Hazara University, Mansehra Pakistan 21300
Abdul Majid, Department of Microbiology, Hazara University, Mansehra Pakistan 21300
Iqbal Ahmad Alvi, Department of Microbiology, Hazara University, Mansehra Pakistan 21300
Azam Hayat, Department of Microbiology, Hazara University, Mansehra Pakistan 21300
Farah Andalee, Department of Microbiology, Hazara University, Mansehra Pakistan 21300
Saira Gul, Department of Microbiology, Hazara University, Mansehra Pakistan 21300
Sabeena Irfan, Department of Microbiology, Hazara University, Mansehra Pakistan 21300
Mujaddad Ur Rahman, Department of Microbiology, Hazara University, Mansehra Pakistan 21300
Received: Dec. 7, 2013;       Published: Dec. 30, 2013
DOI: 10.11648/j.ajbio.20140201.12      View  2949      Downloads  254
Transmission of bacterial strains between patients is a serious problem in hospitals and with the increasing rate of antibiotic resistance the problem has farther escalated. Enterobacteriaceae produced ESBLs, especially E-coli, are increasingly important nosocomial pathogens. These bacteria are often multiple resistant and are responsible for many intestinal infections and urinary tract infections. Urine samples [4010] were collected cultured and the bacterial isolates were identified in this study, 1000 isolates showed significant bacterial growth. Among the sample 1000 showed bacterial growth in which E.coli strains was most common 58.5% of the 1000 bacterial isolates from urine cultures, gram negative rods accounted for 95.30 %, while gram positive cocci accounted for the test 4.70 %. Total pathogen isolated and recovered is distributed as K. pneumoniae 16.7 %, Enterobacter spp 0.57 %, P. aeruginosa 14.5 %, Proteus spp 1.34 % Enterococci 1.05 %, S. aurus 0.76 % and E. faecalis 2.87 %, A. calcoaceticus 1.05 %, Enterobacter spp 0.57 % E. agglumarance 2.20 % serratia 0.1 %. In case of g negative bacteria 58 [2.45 %] were ESBL producers and 379 [47.54 %] were MDR. while in case of gram positive 2 [0.2 %] were MRSA. Resistance has arisen to all antibiotics introduced into general clinical practice and is likely to arise to any new antibiotics introduced in the future. It is therefore imperative to consider what can be done to minimize the development and transfer of antibiotics resistance gene clusters. Methods can be developed to minimize antibiotic resistance.
MDR, ESBL, Bacteria, UTI
To cite this article
Riffat Iqbal, Abdul Majid, Iqbal Ahmad Alvi, Azam Hayat, Farah Andalee, Saira Gul, Sabeena Irfan, Mujaddad Ur Rahman, Multiple Drug Resistance and ESBL Production in Bacterial Urine Culture Isolates, American Journal of BioScience. Vol. 2, No. 1, 2014, pp. 5-12. doi: 10.11648/j.ajbio.20140201.12
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